Application Notes

This application note describes a comparison of a conventional Co-IP protocol with an EXTRACTMAN® protocol using ESP technology. While the conventional Co-IP protocol did not pull down the protein-protein complex, EXTRACTMAN did, demonstrating the utility of ESP technology and EXTRACTMAN.

In this application note, three glucocorticoids and three nonsteroidal anti-inflammatory drugs were detected simultaneously from horse urine using the Gilson GX-274 ASPEC® system with two step extractions and LC/MS/MS selected reaction monitoring (SRM).

Deoxynivalenol (DON) is a mycotoxin that occurs predominantly in grains such as wheat, barley, oats, rye, and maize and consumption is associated with outbreaks of gastroenteritis in humans. Automated methods are well-suited for quantification of toxins because they are accurate, reduce the time required for laboratory analysis, and reduce human errors - learn more in this application note.

Δ9-tetrahydrocannabinol and its metabolites are essential for drug testing. GC/MS is often used for quantification of Δ9-tetrahydrocannabinol, however, it is time consuming. Rapid methods that maintain the sensitivity and selectivity of GC/MS are desirable - learn more in this application note.

Per- and poly-fluoroalkyl substances (PFAs), sometimes referred to as perfluorinated compounds, are a family of molecules consisting of varying lengths of fluorocarbon chains with a functional group such as carboxylic or sulfonic acid attached. This application note describes the automation of the isolation of 10 PFAs from tap water prior to their analysis by LC/MS.

Since 1970, glyphosate has been used as a systemic, non-selective herbicide and crop desiccant on farms, in fields, and in public and residential areas. This application note describes the rapid purification of glyphosate, aminomethylphosphonic acid (AMPA), and glufosinate from red wine using AFFINIMIP® SPE Glyphosate.

This application note describes how PIPETMAX® 268 with qPCR Assistant is a highly proficient pipetting workstation that reduces the potential for cross-contamination and other human induced errors.

This application note describes a high throughput sample preparation procedure for global glycan mass profiling.

Quantitative real time PCR, often coupled with reverse transcription, is a very sensitive technique that can be used for many applications including gene expression analysis. PIPETMAX 268 Normalization Assistant delivers an easy-to-use software and hardware solution to automate normalization of sample concentration without compromising RNA integrity.

Mycotoxins are toxic compounds produced by fungi that are harmful to humans and animals. Patulin, found in rotting apples, is a compound that is regulated in many countries. Food safety testing for patulin is crucial to limit exposure; however, many sample cleanup methods do not remove closely related compounds, which can lead to false positive results.